京尼平

分析標準品,HPLC≥98%

Genipin

CAS號：6902-77-8

分子式：C11H14O5

分子量：226.23

MDL：MFCD00888600

產品介紹

熔點：118.0 - 123.0 ℃

沸點：287.83℃ (rough estimate)

比旋光度：(MeOH)+135

外觀：粉末

溶解性：DMSO:  ≥25mg/mL

敏感性：易吸潮

儲存條件：-20℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(49篇)

49. [IF=4.8] Wang Pei-lu et al."Integrated metabolomics and transcriptomics analysis comprehensively revealed the underlying metabolite mechanism difference between Male and Female Eucommia ulmoides Oliver."BMC PLANT BIOLOGY.2025 Dec;25(1):1-27

48. [IF=11] Ruimin Ran et al."Development of multi-functional collagen films for maintaining and visually monitoring shrimp freshness."FOOD HYDROCOLLOIDS.2025 Mar;160:110734

47. [IF=5.3] Xiaoyu Zhang et al."Elucidating the formation mechanism of gardenia blue pigment from amino acid and genipin."Arabian Journal of Chemistry.2024 Nov;:106048

46. [IF=11] Yun-Yang Zhu et al."Layer-by-layer nanoencapsulation strategies for enhanced oral delivery and function of Lactobacillus plantarum B2."FOOD HYDROCOLLOIDS.2025 Mar;160:110865

45. [IF=7.7] Lingling Sha et al."Genipin-enriched chitosan-Zein nanoparticles for improved curcumin encapsulation."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Dec;:138555

44. [IF=11] Rui Jiang et al."Impact of interfacial rigidity on the rheological properties of high internal phase Pickering emulsions stabilized by casein, walnut protein isolate, and their complexes."FOOD HYDROCOLLOIDS.2025 May;162:111030

43. [IF=7] Jin Feng et al."Interpenetrating network hydrogels loaded with nanostructured lipid carriers for curcumin delivery: Impact of dual crosslinking with genipin and calcium ions."FOOD RESEARCH INTERNATIONAL.2025 Feb;202:115704

42. [IF=11] Lili Zheng et al."Double network hydrogel coating improved avocado freshness preservation: Preparation, testing and mechanism."FOOD HYDROCOLLOIDS.2025 Jun;163:111085

41. [IF=4.7] Ai Gao et al."Covalent binding of Geniposide metabolites to hepatic proteins: A potential mechanism for its hepatotoxicity."CHEMICO-BIOLOGICAL INTERACTIONS.2025 Feb;408:111411

40. [IF=2.3] Yiwan Shi et al."Preparation and osteogenesis of a multiple crosslinking silk fibroin/carboxymethyl chitosan/sodium alginate composite scaffold loading with mesoporous silica/poly (lactic acid-glycolic acid) microspheres."JOURNAL OF BIOMATERIALS APPLICATI

39. [IF=5.5] Kexin Wang et al."Bone ingrowth induced by gelatin/chitosan internal matrix of 3DP Ti6Al4V scaffold."Biomaterials Advances.2024 Aug;:213993

38. [IF=8.5] Chao Zhang et al."Effect of temperature regulation on microbial community, volatile flavours, amino acid profiles, and iridoid glycosides during noni (Morinda citrifolia L.) fruit fermentation."FOOD CHEMISTRY.2025 Jan;462:140966

37. [IF=5.3] Jingjing Yang et al."Exploration on the mechanism of “black as lacquer and sweetness as candy" based on the reactions of “crosslinking coloring and Maillard" and “oligosaccharide hydrolysis" during the processing of Radix Rehmanniae."Arabian Journal of Ch

36. [IF=7.7] Feiyue Ren et al."Preparation, structural characterization, and functional properties of wheat gluten amyloid fibrils-chitosan double network hydrogel as delivery carriers for ferulic acid."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2024 Jul;:1342

35. [IF=5.2] Lijia Li et al."Interpenetrating network based on soybean protein isolate and carboxymethyl chitosan: Investigation of intermolecular reaction mechanism, physicochemical stability and in vitro release properties of the hydrogel."Food Bioscience".2024 Aug;

34. [IF=4.6] Bingxian Zhang et al."Study on the Neuroprotective Effects of Eight Iridoid Components Using Cell Metabolomics."MOLECULES".2024 Jan;29(7):1497

33. [IF=3.9] Yanlong Wu et al."Calcium silicate/gelatin composite scaffolds with controllable degradation behavior: Fabrication and evaluation."Journal of the Mechanical Behavior of Biomedical Materials".2024 Apr;152:106422

32. [IF=8.2] Ziang Tian et al."Lysozyme amyloid fibril-chitosan double network hydrogel: Preparation, characterization, and application on inhibition of Nε-(carboxyethyl)lysine."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 Apr;263:130011

31. [IF=4.1] Aisyah Jaafar et al."Therapeutic potentials of iridoids derived from Rubiaceae against in vitro and in vivo inflammation: A scoping review."SAUDI PHARMACEUTICAL JOURNAL.2023 Nov;:101876

30. [IF=3.4] Ruo-yan Yang et al."Pharmacokinetics, anti-rheumatoid arthritis activity, and active ingredient contents of Eucommia ulmoides Oliv."FITOTERAPIA.10.1016/j.fitote.2023.105667

29. [IF=2.745] Jinling You et al."Establishment of Male and Female Eucommia Fingerprints by UPLC Combined with OPLS-DA Model and Its Application."CHEMISTRY & BIODIVERSITY.2023 Feb;:e202201054

28. [IF=11.504] Lili Zheng et al."Construction and properties of an amyloid fiber ferulic acid chitosan double network hydrogel and its inhibition of AGEs activity."FOOD HYDROCOLLOIDS.2023 May;139:108536

27. [IF=5.123] Yi He et al."Transformation of Gardenia Yellow Waste Production into Gardenia Blue Pigment by Leifsonia sp. ZF2019 and Evaluation of Its Physicochemical Stability."Fermentation-Basel.2022 Oct;8(10):503

26. [IF=6.317] Hongguang Zhu et al."Effect of crosslinking and drying method on the oxidative stability of lipid microcapsules obtained by complex coacervation."Food & Function.2022 Jul;:

25. [IF=5.859] Na Qiao et al."Silk Fabric Decorated with Thermo-Sensitive Hydrogel for Sustained Release of Paracetamol."MACROMOLECULAR BIOSCIENCE

24. [IF=5.717] Man Zhang et al."Dietary Flavone Baicalein Combinate with Genipin Attenuates Inflammation Stimulated by Lipopolysaccharide in RAW264.7 Cells or Pseudomonas aeruginosa in Mice via Regulating the Expression and Phosphorylation of AKT."Nutrients. 2021 Dec;13

23. [IF=6.321] Yujie Zheng et al."Microemulsion Delivery System Improves Cellular Uptake of Genipin and Its Protective Effect against Aβ1-42-Induced PC12 Cell Cytotoxicity."Pharmaceutics. 2022 Mar;14(3):617

22. [IF=3.263] Tianyi Zhao et al."Protective effects of genipin on ethanol-induced acute gastric injury in mice by inhibiting NLRP3 inflammasome activation."Eur J Pharmacol. 2020 Jan;867:172800

21. [IF=4.411] Chunnan Li et al."Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells."Molecules. 2019 Jan;24(21):3920

20. [IF=6.953] Xin Meng et al."Chitosan/alginate/hyaluronic acid polyelectrolyte composite sponges crosslinked with genipin for wound dressing application."Int J Biol Macromol. 2021 Jul;182:512

19. [IF=1.367] Yong Hu et al."Study on the preparation and drug release property of soybean selenoprotein/carboxymethyl chitosan composite hydrogel."J Polym Eng. 2018 Nov;38(10):963-970

18. [IF=3.119] Yingcong He et al."Modifying collagen with alendronate sodium for bone regeneration applications."Rsc Adv. 2018 May;8(30):16762-16772

17. [IF=3.267] Yu Qian et al."Lactobacillus casei Strain Shirota Enhances the In Vitro Antiproliferative Effect of Geniposide in Human Oral Squamous Carcinoma HSC-3 Cells."Molecules. 2018 May;23(5):1069

16. [IF=4.142] Ji  Wenhua et al."Superhydrophilic molecularly imprinted polymers based on a single cross-linking monomer for the recognition of iridoid glycosides in Di-huang pills."Anal Bioanal Chem. 2018 Oct;410(25):6539-6548

15. [IF=4.223] Wang  Ruihua et al."UCP2- and non-UCP2-mediated electric current in eukaryotic cells exhibits different properties."Environ Sci Pollut R. 2015 Dec;22(24):19618-19631

14. [IF=4.759] Wenhua Ji et al."Water-compatible micron-sized monodisperse molecularly imprinted beads for selective extraction of five iridoid glycosides from Cornus officinalis fructus."J Chromatogr A. 2017 Jun;1504:1

13. [IF=4.759] Lu Wang et al."A strategy for identification and structural characterization of compounds from Gardenia jasminoides by integrating macroporous resin column chromatography and liquid chromatography-tandem mass spectrometry combined with ion-mobility spectr

12. [IF=10.652] Shan Zhang et al."Mass-production of fluorescent chitosan/graphene oxide hybrid microspheres for in vitro 3D expansion of human umbilical cord mesenchymal stem cells."Chem Eng J. 2018 Jan;331:675

11.  Wang, Ruihua et al. “A Mechanism for the Temporal Potentiation of Genipin to the Cytotoxicity of Cisplatin in Colon Cancer Cells." International journal of medical sciences vol. 13,7 507-16. 29 Jun. 2016, doi:10.7150/ijms.15449

10.  Wang, Ruihua et al. “A Mechanism for the Temporal Potentiation of Genipin to the Cytotoxicity of Cisplatin in Colon Cancer Cells." International journal of medical sciences vol. 13,7 507-16. 29 Jun. 2016, doi:10.7150/ijms.15449

9.  Lu, Zhi Hua, Chun Guang Yin, and Dong Mei Zhao. "Biomimetic scaffolds containing chitosan and hydroxyapatite for bone tissue engineering." Advanced Materials Research. Vol. 971. Trans Tech Publications Ltd, 2014.https:##doi.org/10.4028/www.scientific。。ｎｅｔ/A

8.  Jiao, Yanting, et al. "Genipin, a natural AKT inhibitor, targets the PH domain to affect downstream signaling and alleviates inflammation." Biochemical pharmacology 170 (2019): 113660.https:##doi.org/10.1016/j.bcp.2019.113660

7.  Zhang, Shan, et al. "Mass-production of fluorescent chitosan/graphene oxide hybrid microspheres for in vitro 3D expansion of human umbilical cord mesenchymal stem cells." Chemical Engineering Journal 331 (2018): 675-684.https:##doi.org/10.1016/j.cej.2017.0

6.  Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism." Molecules 21.5 (2016): 597.https:##doi.org/10.3390/molecules21050597

5.  劉錕,王健英,魏莉,潘穎宜,袁穎.HPLC法測定杜仲皮、葉、雄花中8種成分[J].中成藥,2021,43(03):686-691.

4.  劉蔚  常杰  武毅君 等. 健骨痛消丸中活性成分的檢測及其抗凝血作用的研究[J]. 河南大學學報（醫學版） 2020年39卷2期  80-84頁  2020.

3.  馮家懿, 張圳, 果卉,等. 藥學本科藥物分析的課外科研實踐探索[J]. 廣州化工, 2018, 046(002):128-130.

2.  陳星光, 鄒承達, 宿廣昊,等. 負載富血小板纖維蛋白的新型水凝膠對BMSCs體外成軟骨分化的影響[J]. 江蘇大學學報(醫學版), 2018, v.28；No.142(04):20-25.

1.  劉涵  尹子楚  蔡玉榮 等. 絲素蛋白/多巴胺醫用粘合劑的制備及其性能[J]. 浙江理工大學學報  2020  043(003):308-314.